Program

Welcome and Opening Remarks

Robert L. Ferris, MD, PhD, FACS

Director of UPMC Hillman Cancer Center

Symposium Overview

SPCIG Organizing Committee

Riyue Bao, PhD, Tullia C. Bruno, PhD, and Yufei Huang, PhD

Overcoming the segmentation barrier in multiplexed spatial proteomic images

Shikhar Uttam, PhD — University of Pittsburgh

Molecular Signatures of Hippocampal Tau Pathology in Neurodegeneration

Meaghan O'Malley Morris, MD, PhD — Johns Hopkins University

Spatially resolved analysis of breast cancer tumor immune microenvironment

Hatice U. Osmanbeyoglu, MS, PhD — University of Pittsburgh

Emerging stars: Uncovering molecular heterogeneity of mixed ductal and lobular carcinomas using digital spatial profiling

Osama Shiraz Shah, Integrative System Biology PhD Program, Y5

Lee & Oesterreich Lab — University of Pittsburgh

Keynote: Machine learning discovery of spatial cellular motifs and treatment interactions for precision oncology

James Zou, PhD — Stanford University

Moderator: Yufei Huang, PhD

* Dr. Zou will join us virtually via Zoom.

An editor's thoughts on publishing reproducible microscopy methods and the future of bioimage analysis

Rita Strack, PhD — Nature Methods, Senior Editor

* Dr. Strack will join us virtually via Zoom.

Integrative single-cell spatial modeling of cell identity

Jian Ma, PhD — Carnegie Mellon University

Emerging stars: In vitro modeling of tumor-CD8+ T cell interactions in HER2+ breast cancer

Ruxuan (Rosy) Li, Bioengineering PhD Program, Y3

Zervantonakis Lab — University of Pittsburgh

Closing Remarks

Riyue Bao, PhD — UPMC Hillman Cancer Center

Lunches available in the Atrium, across from the Auditorium. Please proceed to your designated break out room with your lunch.

Breakout room 1 location: 2001. Directions: take the elevator to 2nd floor, once exit from the elevator, turn right, the room is directly ahead [ note that the door does not have room number shown ]

Breakout room 2 location: B1610. Directions: take the elevator to basement floor, once exit from the elevator, the room is directly across the hallway from the elevator

Breakout room 1 (concurrent): Room 2001

Nanostring DSP GeoMx and 10x Genomics Visium

Tullia C. Bruno, PhD and Amanda C. Poholek, PhD

Breakout room 2 (concurrent): Room B1610

Computational Solutions for Spatial Technologies

Riyue Bao, PhD and Yufei Huang, PhD